S.R. 772 is closed at Rinehart Road, four miles south of Chillicothe, due to a water main break.
As of 4:00 p.m. Wednesday, ODOT said they were unsure how long the duration of the closure would be, adding that motorists will need to seek alternate routes or detour via U.S. 23.
However, ODOT says U.S. 35 West in Ross County has been reopened at the U.S. 50 interchange following a vehicle fire earlier this afternoon.